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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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药物开发 药物开发

Tianhua Zhai1, David Shen2, Magally Arevalo Navarro3

  • 1Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

集结结合和QSAR特征的机器学习模型改善了Beta-secretase 1 (BACE1) 抑制剂结合亲和力的预测. 这加速了新的阿尔茨海默病 (AD) 治疗方法的发现.

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