临床表现 临床表现
Sydney Y Schaefer1, Michael H Malek-Ahmadi2,3, Angela Kuramoto4
1Arizona State University, Tempe, AZ, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
概括
日常生活和认知活动简要评估 (BEAN) 测试测量认知,而不是身体活动. 认知参与,而不是身体活动,改善了老年人的认知能力.
科学领域:
- 老年学是指老年学的学科.
- 认知神经科学 认知神经科学
- 行为科学 行为科学
背景情况:
- 众所周知,认知和体力活动可以降低老年人痴呆风险.
- 日常生活和认知活动简要评估 (BEAN) 测试是使用对象操纵进行基于绩效的评估.
- 需要澄清BEAN测试与认知和日常运作的关系的调解机制 (认知与物理).
研究的目的:
- 调查BEAN测试与认知功能和日常活动的关联是否通过认知参与或身体活动进行调解.
- 为了确定BEAN测试是否更能反映老年人的认知能力或身体能力.
主要方法:
- 290名50岁以上没有认知障碍的社区成年人参与了这项研究.
- 参与者完成了BEAN测试,蒙特利尔认知评估 (MoCA),身体活动快速评估 (RAPA) 和认知刺激活动问卷 (CSA-Q).
- 使用通用线性混合模型和调解分析分析了横截面数据.
主要成果:
- BEAN测试得分与MoCA得分 (认知) 和CSA-Q得分 (认知活动) 有显著的相关性.
- 调解分析表明,认知参与 (CSA-Q) 调解了BEAN测试和MoCA分数之间的关系.
- 在BEAN测试和RAPA分数 (体育活动) 之间没有发现显著的关系,RAPA也没有调解BEAN-MoCA关系.
结论:
- BEAN测试是认知和日常运作的有效衡量标准,而不是身体或运动评估.
- 认知参与,而不是身体活动,似乎是BEAN测试反映老年人认知益处的关键机制.
- 这些发现支持了BEAN测试在理解认知参与如何影响老龄人口认知方面的有用性.
相关概念视频
Chronic Kidney Disease II: Clinical Manifestations
520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations
299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis
364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations
436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management
652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies
437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437


