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Updated: Jan 7, 2026

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药物开发 药物开发

Fernando Goni1, Ding Wang1, Jianina Suazo1

  • 1NYU Grossman School of Medicine, New York, NY, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括

针对粉样β寡合体的两种IgM抗体,GW-23B7和WG-3D7,在阿尔茨海默病 (AD) 鼠标模型中显示出显著的认知救援. 这些AβComAbs在不引起炎症或微出血的情况下降低了Aβ病理,这表明人类安全临床试验的潜力.

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