怀孕前父亲戒烟可以降低自发流产的风险:基于人口的回顾性队列研究
Ziyi Cheng1, Ying Yang2, Sijing Ding1
1Institute of Epidemiology and Statistics, School of Public Health, Lanzhou University, Lanzhou, Gansu, China.
Journal of epidemiology and community health
|December 25, 2025
概括
怀孕前父亲戒烟可以降低自发流产的风险. 然而,与非父亲吸烟相比,SAB风险仍然更高,这凸显了父亲戒烟的重要性.
科学领域:
- 生殖健康 生殖健康
- 围产期结局的结果
- 公共卫生 公共卫生
背景情况:
- 父亲吸烟对怀孕的不良影响是公认的.
- 怀孕前父亲戒烟的健康益处还没有得到充分的研究.
研究的目的:
- 调查父亲在怀孕前戒烟与自发流产 (SAB) 风险之间的联系.
主要方法:
- 该研究包括来自中国国家免费妊娠前检查项目 (2010-2018) 的158,986例怀孕.
- 主要暴露:怀孕前父亲戒烟.
- 主要结局:自发流产 (SAB).
- 统计分析:逆概率加权 (IPW) 逻辑回归和仪器变量 (IV) 分析.
主要成果:
- 在怀孕之前父亲戒烟与SAB风险降低有关 (IPW OR 0.86;IV OR 0.79).
- 减少父亲吸烟也与较低的SAB风险相关.
- 与没有吸烟的父亲相比,父亲戒烟后SAB风险仍然更高 (IV OR 1.21).
结论:
- 怀孕前父亲戒烟与自发流产风险降低有关.
- 预孕咨询应该强烈建议吸烟的父亲戒烟,以改善怀孕结果.
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