Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Feynman Kac Reweighted Schrödinger Bridge Matching for Surface-Based Tau PET Harmonization.

ArXiv·2026
Same author

Reallocating 24-hour movement behaviors and cardiometabolic health in adults: a systematic review and meta-analysis.

Archives of public health = Archives belges de sante publique·2026
Same author

GPU Accelerated Modeling of Cortical Radial and Tangential Connectivity Changes in Neurodegeneration.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention·2026
Same author

Robust Topographical Representation for Longitudinal Propagation of Tau Pathology.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention·2026
Same author

Circadian rhythms regulate osteoclast recycling through gut microbiota-dependent Th17 cell expansion.

Current research in microbial sciences·2026
Same author

Graphical modeling of cortical tau pathology topography for its subtyping in Alzheimer's disease.

Imaging neuroscience (Cambridge, Mass.)·2026
Same journal

Evidence for progressive neurodegeneration in iatrogenic cerebral amyloid angiopathy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Kat5 cKO mouse replicates biological domain signatures associated with Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Evaluation of CSF and plasma tau species as fluid surrogate candidates for tau PET in prodromal to moderate Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Associations of self-reported obstructive sleep apnea with cognition and dementia risk in cognitively unimpaired middle-aged adults.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Inflammation profiles in Alzheimer's disease relate to cognition and neurodegeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Shuo Ni1, Jiaxin Yue2, Yonggand Shi3

  • 1University of Southern California, Los Angeles, CA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括
此摘要是机器生成的。

像PI-2620这样的第二代TAU-PET标记剂对评估阿尔茨海默氏病 (AD) 中的皮质下TAU病理有希望. 种族影响这些TAU PET信号,特别是在非西班牙裔白人个体的杏仁体.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经成像是一种神经成像.
  • 神经学 神经学
  • 阿尔茨海默氏症疾病研究研究

背景情况:

  • 第一代TAU-PET标记剂 (例如AV-1451) 由于在皮层下区域的非目标结合而存在局限性.
  • 第二代标记剂 (例如PI-2620,MK-6240) 为皮层下病理提供了更好的特异性.
  • 在皮下阿尔茨海默氏症 (AD) 研究中评估新型tau PET标记物的实用性至关重要.

研究的目的:

  • 评估PI-2620PET追踪器在检测阿尔茨海默病 (AD) 中皮下病理方面的有效性.
  • 调查种族对皮层下皮质PET信号在认知不受损 (CU) 和认知受损 (CI) 个体的影响.
  • 为了检查在特定的皮层下大脑结构内的诊断类别和种族之间的TAU PET信号的差异.

主要方法:

  • 在健康和衰老大脑研究:健康差异 (HABS-HD) 队列中利用PI-2620标记器的tau PET数据.
  • 包括1,492名参与者 (1097CU,395CI) 进行T1加权MRI和tau PET成像,包括多个不同的种族群体.
  • 计算的平均标准化摄入值比 (SUVR) 对皮下区域 (大脑皮层,尾皮层,皮层等) 的平均标准化摄入值比. 使用FreeSurfer细分的方法.

主要成果:

  • 在诊断类别的尾状体,海马体和杏仁体中发现了tau SUVR的显著差异.
  • 在认知不受损和认知受损组之间观察到皮层下皮质PET信号的种族差异.
  • 非西班牙裔白人参与者在骨,海马和杏仁体中表现出显著的差异;黑人参与者在尾状体中;西班牙裔参与者在杏仁体中.

结论:

  • 种族显著影响在认知上不受损的和受损的个体中的皮质下皮质PET信号.
  • PI-2620标记器显示了在不同人群中评估皮质下病理的潜力.
  • 在阿尔茨海默病中,特定的皮层下区域,如杏仁体,表现出受种族影响的差异性积.