Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Dementia risk prediction in individuals with mild cognitive impairment: a comparison of Cox regression and machine learning models.

BMC medical research methodology·2022
Same author

What does aducanumab treatment of Alzheimer's disease mean for research on vascular cognitive disorders?

Cerebral circulation - cognition and behavior·2022
Same author

White matter hyperintensities and mild behavioral impairment: Findings from the MEMENTO cohort study.

Cerebral circulation - cognition and behavior·2022
Same author

Acute Infarcts on Brain MRI Following Aortic Arch Repair With Circulatory Arrest: Insights From the ACE CardioLink-3 Randomized Trial.

Stroke·2022
Same author

The global burden of cerebral small vessel disease in low- and middle-income countries: A systematic review and meta-analysis.

International journal of stroke : official journal of the International Stroke Society·2022
Same author

Unraveling the Protective Effects of Cognitive Reserve on Cognition and Brain: A Cross-Sectional Study.

International journal of environmental research and public health·2022
Same journal

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Estimated labor market outcomes of people progressing from preclinical to early-stage Alzheimer's disease in the United States.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Amyloid exacerbates tau and alpha-synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Reply to "Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Maryam Ghahremani1, Rebeca Leon1, Eric E Smith1,2

  • 1Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括
此摘要是机器生成的。

轻度行为障碍 (MBI) 与较高的血p-tau217水平有关,这表明MBI可能表明阿尔茨海默病 (AD) 蛋白质病变. 这一发现支持MBI在早期AD检测和风险分层方面的作用.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经科学是一个神经科学.
  • 生物标志物 生物标志物
  • 老年学是指老年学的学科.

背景情况:

  • 2024年NIA-AA标准使用粉样β和生物标志物定义了阿尔茨海默病 (AD).
  • 轻度行为障碍 (MBI),以持续的神经精神症状为特征,可能会先于认知能力下降,并表明痴呆风险.
  • 目前,MBI与血p-tau217,AD病理学的新型血液生物标志物之间的关联尚未被探索.

研究的目的:

  • 调查老年人MBI和血p-tau217水平之间的关联.
  • 探索MBI作为潜在的AD相关病理的早期指标,使用血p-tau217.7.

主要方法:

  • 在两次访问中使用神经精神科目录评估神经精神病症状 (NPS) 来确定MBI状态.
  • 利用线性和逻辑回归来建模MBI状态与血p-tau217水平之间的关联.
  • 根据阿尔茨海默氏病神经成像计划参与者的年龄,性别,教育和认知诊断进行调整的模型.

主要成果:

  • 与没有MBI的参与者相比,MBI的参与者表现出明显更高的血p-tau217水平.
  • 患有MBI的个体显示出患有血p-tau217水平升高 (阳性) 的几率增加.
  • 该研究包括101名参与者 (平均年龄为72.0±6.5岁;44.6%是女性;50.5%有轻度认知障碍).

结论:

  • MBI与血p-tau217的升高有关,支持其在代表AD蛋白质病变中的作用.
  • MBI评估可能有助于在临床试验中早期发现AD和风险分层.
  • 研究结果强调了MBI在识别具有AD生物标志物阳性个体方面的潜在实用性.