Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

746
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
746
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

511
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
511

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Brain regional susceptibility to tauopathy in individuals at risk for chronic traumatic encephalopathy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Dose-dependent white matter changes associated with repetitive head impacts in former American football players.

Brain communications·2026
Same author

Cognitive, biomarker, and neuroimaging indices associated with traumatic encephalopathy syndrome across two independent athlete cohorts.

Alzheimer's research & therapy·2026
Same author

The word Dementia should be retired.

Communications medicine·2026
Same author

A plasma protein signature for cerebral amyloid angiopathy.

Acta neuropathologica·2026
Same author

Advancing biomarker development for chronic traumatic encephalopathy: Summary and recommendations from the 2025 Leon Thal Summit.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Breaking barriers: Enhancing access to dementia clinical trials in the United Kingdom-Insights from the Scientific Advisory Board of the Dame Barbara Windsor Dementia Goals Programme.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Estimated labor market outcomes of people progressing from preclinical to early-stage Alzheimer's disease in the United States.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Amyloid exacerbates tau and alpha-synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Reply to "Shifting the emphasis of brain health literacy from individuals to systems to reduce inequalities".

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Yiming Che1,2, Ziqi Guo3, Jay Shah1,2

  • 1Arizona State University, Tempe, AZ, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括
此摘要是机器生成的。

一个新的Cycle-GAN模型使用未配对的训练数据协调神经成像数据,在选择最小的配对数据的情况下显著改善结果. 这种方法提高了PET成像分析的数据通用性.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

699

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

699

科学领域:

  • 神经成像是一种神经成像.
  • 机器学习 机器学习
  • 医疗数据分析 医学数据分析

背景情况:

  • 协调正子发射断层扫描 (PET) 成像数据,如匹兹堡化合物-B (PiB) 和氧糖-PET (FDG-PET),对于准确的分析至关重要.
  • 传统的协调方法通常需要大量的配对数据,这些数据可能很难或不可能获得.
  • 现有的未配对方法可能缺乏复杂医疗数据集所需的通用性.

研究的目的:

  • 为神经成像数据开发和验证一种基于Cycle-GAN的新型协调模型.
  • 为了消除在模型训练期间需要大量配对数据的需求,使用未配对数据代替.
  • 提高PET成像数据协调的普遍性和性能.

主要方法:

  • 一个循环-GAN模型适用于表式神经成像数据,修改生成器和区分器使用多层感知子 (MLP) 和跳过连接.
  • 该模型使用大量未配对的PiB和FBP测量数据集进行训练 (可能FBP是另一种PET追踪器或成像模式).
  • 一小部分配对数据用于模型选择,通过皮质平均标准化摄取值比率 (mcSUVR) 的皮尔森相关性来评估性能.

主要成果:

  • 选择的循环-GAN模型在协调的PiB数据和实际的PiB数据之间实现了高的皮尔森相关性 (0.85),超过了基线.
  • 统计分析 (施泰格的Z测试) 证实了与基线方法相比的显著改善 (p < 0.0001).
  • 添加了诸如CL和人口统计数据 (年龄,性别) 等额外的特征,进一步改善了协调结果.

结论:

  • 一个基于Cycle-GAN的协调模型成功地开发了未配对的神经成像数据.
  • 该模型展示了培训协调模型的可行性,其中主要是未配对的数据,只需要一个小的子集进行选择.
  • 在PiB和FBP测量方面取得了有希望的协调结果,这表明在神经成像分析中更广泛的应用潜力.