临床表现 临床表现
Marnina B Stimmel1, Emmeline Ayers2, Joe Verghese2
1Albert Einstein College of Medicine, Bronx, NY, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
概括
阿登布鲁克认知检查III (ACE-III) 的某些项目显示,在印度的认知正常的马来拉语老年人中,特别是那些受教育程度较低的人中,错误率很高. 这些发现表明,在这个人群中对ACE-III结果的解释要谨慎.
科学领域:
- 神经学 神经学
- 认知科学 认知科学
- 老年学是一门学科.
背景情况:
- 全球痴呆率的上升需要经过验证的认知查工具.
- 阿登布鲁克认知检查-III (ACE-III) 是用于识别认知障碍的广泛使用的工具.
- 之前的研究表明,特定的ACE-III项目存在潜在问题,特别是关于教育成就的问题.
研究的目的:
- 评估在印度认知正常的马来拉语老年人队伍中个别ACE-III项目的表现.
- 为了确定在这个群体中可能产生高错误率的特定ACE-III项目.
- 调查教育水平对个人ACE-III项目的表现的影响.
主要方法:
- 来自喀拉拉邦爱因斯坦研究的132名马来拉语老年人参加了这项研究.
- 参与者接受了马来拉语版本的ACE-III和全面的神经心理电池.
- 认知正常性是通过专家的共识来确定的;教育是二分化的 (≥10年 vs <10年) 进行分析.
主要成果:
- 一些ACE-III项目得到了普遍认可 (例如,导向,重复,理解).
- 超过25%的参与者在诸如时钟绘图,立方体复制和名字/地址回忆等项目上犯了错误.
- 较低的教育程度与特定ACE-III项目的更高的错误率有显著的关联.
结论:
- ACE-III是一个有价值的查工具,但某些项目在认知正常的马来拉语老年人中显示出有限的实用性.
- 特定项目的高错误率,特别是那些教育程度较低的人,需要谨慎的解释.
- 这些发现强调了在解释ACE-III表现时需要考虑教育背景的必要性,以避免误诊.
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