Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Validated Measures of Agitation in Neurocognitive Disorders: A Systematic Review of 41 Scales and Their Alignment With International Psychogeriatric Association Criteria.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·2026
Same author

Spermidine in Alzheimer's Disease: Evidence from Animal Models and Human Studies.

Degenerative neurological and neuromuscular disease·2026
Same author

Willingness and barriers to blood-based biomarker testing of Alzheimer's disease in the general population in the Czech Republic.

Alzheimer's research & therapy·2026
Same author

Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer's disease pathology.

Nature aging·2026
Same author

Associations of lifestyle and health factors with subjective memory complaints in a large cohort of mHealth users.

Aging & mental health·2026
Same author

Challenging memory tests in early Alzheimer's disease: From research to clinical practice.

Neuroscience and biobehavioral reviews·2026

相关实验视频

Updated: Jan 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.4K

临床表现 临床表现

Monika Krejci1,2, Veronika Matuskova2, Toni T Saari3

  • 1Charles University, Faculty of Arts, Prague, Czech Republic.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
PubMed
概括
此摘要是机器生成的。

早期神经退行性疾病中的神经精神症状 (NPS) 最好通过将患者的自我报告与告知者的观点相结合来评估. 告知者评级与认知缺陷更好地相关,有助于早期诊断.

更多相关视频

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

6.1K

相关实验视频

Last Updated: Jan 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.4K
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

6.1K

科学领域:

  • 神经科学是一个神经科学.
  • 老年学是一门学科.
  • 精神病学是一个精神病学.

背景情况:

  • 认知缺陷中的神经精神症状 (NPS) 通常是告知者评估的.
  • 患者的自我感知提供了宝贵的见解,特别是在神经退行性疾病的早期阶段.
  • 之前的研究表明,自我报告和告密者报告的NPS之间存在差异.

研究的目的:

  • 通过使用轻度行为障碍检查清单 (MBI-C) 分析自我和告密者评级NPS的差异.
  • 检查NPS与认知缺陷程度之间的关联.
  • 为了比较主观认知衰退 (SCD) 和轻度认知障碍 (MCI) 患者的自我和告知者评级的NPS.

主要方法:

  • 招募了127名患有认知障碍的非痴呆老年人和他们的告知者.
  • 参与者被分为SCD (N=38),MCI (N=89) 和对照 (N=26) 组.
  • 自我和告密者填写的捷克MBI-C被分析了与认知的差异和相关性.

主要成果:

  • 与对照组相比,SCD和MCI组的自我和告密者MBI-C分数都较高.
  • 告知者评级显示,与自我评级相比,与认知缺陷 (记忆力,执行功能) 的关联更强.
  • 在MCI组中,提供信息的人报告了更严重的冲动控制问题.

结论:

  • 自我和告密者评级的NPS评估对于早期神经退行性疾病诊断至关重要.
  • 有信息的见解将NPS与认知缺陷联系起来,而自我报告捕捉主观经验.
  • 结合这两种观点,可以提供诊断的补充数据.