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Updated: Jan 7, 2026

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IGF2BP3-STAT3-METTL3轴促进肝细胞癌 (HCC) 的恶性进展

Yang Xu1,2, Yu Cao2, Jingbo Yang1,3

  • 1First Central Hospital of Tianjin Medical University, Tianjin, 300070, China.

Human genomics
|December 25, 2025
PubMed
概括

胰岛素样生长因子2 mRNA结合蛋白3 (IGF2BP3) 通过稳定IL4R mRNA和激活JAK2-STAT3通路,促进肝细胞癌 (HCC). 这一途径协调了N6-甲基氨酸 (m6A) 在HCC进展中的修饰.

关键词:
在HCC中,HCC是HCC,HCC是HCC.在 IGF2BP3BP3 中.在 IL4R 中, IL4R 是 IL4R 的代名词.在METTL3中,METTL3是METTL3的第一个类型.在WTAP中,使用的是WTAP.

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