临床表现 临床表现
Sophia L Holmqvist1, Riya Chaturvedi1, Marina Kaplan1
1Temple University, Philadelphia, PA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
概括
通过生态瞬间评估 (EMA) 测量的日常情绪和主观认知与老年人对抑郁症,认知衰退和功能的传统评估相关. 主观认知,但不是情绪,与客观认知表现相关.
科学领域:
- 老年学是一门学科.
- 认知神经科学 认知神经科学
- 精神病学是一个精神病学.
背景情况:
- 抑郁症状经常与老年人自我报告的认知能力下降有关.
- 传统的评估在一个点上捕捉情绪和功能,可能会错过每天的波动.
- 生态瞬间评估 (EMA) 提供了一种捕捉情绪和主观认知的日常变化的方法.
研究的目的:
- 探索日常情绪,主观认知和老年人抑郁症,认知衰退和功能常规措施之间的关系.
- 调查EMA在评估现实环境中的情绪和认知方面的实用性.
主要方法:
- 55名居住在社区的老年人 (健康的认知或轻微的认知障碍) 完成了为期30天的基于智能手机的EMA调查,评估日常情绪和主观认知.
- 基线评估包括认知测试,老年抑郁量表-15 (GDS),日常认知测量 (Ecog) 和功能活动问卷 (FAQ).
- 使用斯皮尔曼相关性来分析EMA数据和基线措施之间的关联.
主要成果:
- 较高的中性情绪日和较低的快乐日百分比与更高的GDS分数相关.
- 增加"不敏"的主观认知日与更大的自我报告认知衰退 (Ecog) 和功能困难 (FAQ) 有关.
- 较高的"不清晰"天的百分比和较低的Ecog分数与较低的客观认知复合分数和较高的GDS分数有关.
结论:
- 每日EMA对情绪和主观认知的测量与老年人的传统临床评估一致.
- 通过EMA和传统方法评估的主观认知,证明了与客观认知表现的关系,与情绪不同.
- EMA是捕捉现实世界情绪和老年人的认知经验的有效工具,支持使用传统措施.
相关概念视频
Chronic Kidney Disease II: Clinical Manifestations
520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations
299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis
364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations
436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management
652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies
437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437


