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光声学显微镜用于多尺度生物系统可视化和临床翻译

Tingting Wang¹, Jiali Chen², Liming Nie²

¹Department of Traditional Chinese Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

|December 26, 2025

概括

光声学显微镜 (PAM) 提供非侵入性,高分辨率的深层组织成像. 最近的技术进步和人工智能集成正在为其在精准医学中的临床转化铺平道路.

科学领域:

生物医学成像技术生物医学成像技术
光声学物理学的物理学
医疗技术医疗技术医学技术

背景情况:

光声显微镜 (PAM) 提供非侵入性,高分辨率的成像,具有卓越的光学对比度.
PAM利用超声波信号进行深层组织可视化,超越纯光学方法的局限性.
本综述综合了最近的PAM进展,应用和临床翻译途径.

研究的目的:

审查技术创新和PAM的应用.
探索PAM在临床转化中的潜力.
确定PAM发展的局限性和未来方向.

主要方法:

审查PAM技术的最新进展,包括扫描仪,传感器,AI算法和分子剂.
在单细胞分析,微循环,脏清除,瘤检测和神经科学中对器官特异性应用的调查.
分析未来临床用途和持续存在的局限性.

主要成果:

通过高速扫描仪,阵列传感器,AI算法和分子剂来增强PAM性能.
PAM显示了多种应用,包括单细胞分析和瘤转移检测.
临床翻译对手术内指导和护理点诊断有前途.

结论:

PAM是一种多功能工具,具有临床应用的巨大潜力.
未来的进步需要多式联运一体化,人工智能和标准化的协议.
PAM准备成为精准医学中的临床支柱.

关键词:

生物医学应用程序临床翻译临床翻译摄影声学显微镜的使用方法精准医学是一门精准医学.技术的进步是技术的进步.

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