Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Developing a core outcome set (COS) for Dementia with Lewy bodies (DLB).

HRB open research·2023
Same author

Research diagnostic criteria for mild cognitive impairment with Lewy bodies: A systematic review and meta-analysis.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2023
Same author

Dementia with Lewy Bodies Drug Therapies in Clinical Trials: Systematic Review up to 2022.

Neurology and therapy·2023
Same author

Levels of Loneliness and Mental Health in Older Adults across Ethnic Groups During the COVID-19 Pandemic in the UK.

Journal of the American Medical Directors Association·2023
Same author

Between-person and within-person effects in the temporal relationship between depressive symptoms and cognitive function.

Journal of affective disorders·2023
Same author

The impact of low dementia research funding on brain health for decision makers: A reflection on current health statistics.

Journal of the neurological sciences·2023

相关实验视频

Updated: Jan 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.4K

临床表现 临床表现

Ta-Wei Guu1,2, Dag Aarsland3,4, Dominic H Ffytche5

  • 1Division of Psychiatry, Department of Internal Medicine, China Medical University Beigang Hospital, Yunlin, Taiwan.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
PubMed
概括
此摘要是机器生成的。

与传统问卷相比,可穿戴设备Actigraphy提供了更敏感的睡眠障碍和阿尔茨海默病患者的不规则性测量方法. 这项技术可以补充现有方法,并确定激动和睡眠问题的新治疗点.

更多相关视频

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

6.1K

相关实验视频

Last Updated: Jan 7, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

16.4K
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.7K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

6.1K

科学领域:

  • 老年学是一门学科.
  • 神经科学是一个神经科学.
  • 生物医学工程 生物医学工程

背景情况:

  • 睡眠障碍和痴呆症 (BPSD) 的夜间行为和心理症状在阿尔茨海默病 (AD) 患者中普遍存在并具有挑战性.
  • 目前的测量方法依赖于潜在的不准确的护理者评级问卷.
  • 这项研究研究了动图学和GGIR R包对于AD晚期的客观睡眠测量的实用性.

研究的目的:

  • 为了评估动态图的有效性,以测量晚期阿尔茨海默病的养老院居民的睡眠模式.
  • 为了将动图学衍生的睡眠数据与传统的基于问卷的评估 (NPI-NH,PSQI) 进行比较.
  • 探索睡眠参数和兴奋症状之间的相关性.

主要方法:

  • 利用Geneactiv原始的动图装置和GGIR R包用于STAND试验中的28名参与者的睡眠分析.
  • 在基线,第2周和第4周使用护理人员评级的NPI-NH和PSQI评估BPSD.
  • 使用斯皮尔曼相关性和线性回归来分析基于设备的睡眠变量与问卷数据.

主要成果:

  • 在所有测量工具中观察到睡眠问题的高患病率.
  • 动图显示睡眠规律指数始终较低,对时间依赖的变量比问卷更敏感.
  • 在Wake-After-Sleep-Onset (WASO) 持续时间和易怒性之间发现了适度的相关性.

结论:

  • 在这种AD人群中,夜间睡眠经常很差,不规则,不规则可能会被调查问卷遗漏.
  • 穿戴式行为摄影提供了一个有价值的,客观的测量工具,以补充临床试验中的现有方法.
  • 动图学数据可能为AD的睡眠障碍和兴奋症的新疗法目标提供见解.