痴呆症护理研究和心理社会因素
Karishma R Ramdeo1, Aimee J Nelson1
1McMaster University, Hamilton, ON, Canada.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
概括
针对运动皮层的重复性横磁刺激 (rTMS) 改善了痴呆症患者的平衡和认知能力. 这种加快的间歇性甲基突发刺激 (aiTBS) 与平衡训练相结合,对管理阿尔茨海默病症状有很大希望.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 康复医学 康复医学 康复医学
背景情况:
- 认知障碍增加了跌倒风险;失衡是关键指标.
- 平衡控制可以作为一个生物标志物用于老龄化人口的认知衰退.
研究的目的:
- 调查加速重复性横磁刺激 (rTMS) 方案是否可以提高痴呆症和阿尔茨海默病患者的认知和平衡.
- 评估针对不同大脑区域 (M1,DLPFC) 的rTMS与平衡训练相结合的疗效.
主要方法:
- 在14天内,每天都采用加速间歇性甲基突发刺激 (aiTBS) 方案.
- 参与者接受了针对主要运动皮质 (M1),背侧前额皮质 (DLPFC) 或安慰剂的rTMS.
- 在aiTBS之后进行了基于生物反的平衡训练,重点是体重转移能力.
主要成果:
- 针对M1的rTMS组在平衡评估 (稳定性极限,平衡和跌倒风险) 中表现出显著的改善.
- 通过MoCA测量认知功能,与DLPFC和安慰剂相比,M1组的认知功能也显著改善.
- 这项研究介绍了aiTBS和平衡训练的首个组合,用于增强认知和平衡.
结论:
- 结合 aiTBS 和平衡训练方法,可以改善痴呆症和阿尔茨海默病患者的平衡和认知能力.
- 将aiTBS与平衡培训一起针对M1地区似乎特别有效.
- 这种新的治疗策略可能为控制神经退行性疾病症状提供临床益处.
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