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药物开发 药物开发

Samar Padder1, Whitaker Cohn1, Jesus J Campagna1

  • 1University of California, Los Angeles (UCLA), Los Angeles, CA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
PubMed
概括

研究人员在阿尔茨海默氏症 (AD) 模型中发现了新型的小分子,可以提高神经保护性分泌集群蛋白 (sCLU) 的水平. 化合物DL-357减少了tau病理和改善了记忆力,为AD提供了一个有前途的新治疗策略.

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