遗传相关性和门德尔随机化分析揭示了代谢相关疾病或风险因素与主要眼睛疾病之间的因果关系

Jialing Tang1, Junjie Chen2, Zhaohuai Li2

  • 1State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Current eye research
|December 26, 2025
PubMed
概括

高血压导致白内障风险增加,尤其是老年白内障. 低密度脂蛋白 (LDL) 胆固醇可以防止与年龄相关的黄斑变性 (AMD),而高密度脂蛋白 (HDL) 胆固醇会增加AMD的风险. 2型糖尿病 (T2D) 显示出与白内障和绿内障的遗传联系.

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