益生菌补充剂和注意力缺陷/多动障碍儿童的执行功能
Abdolrahman Parhiz1, Pegah Samani2, Majid Kamali3
1Kish International Campus, University of Tehran, Tehran, Iran.
Neuropsychopharmacology reports
|December 26, 2025
概括
益生菌补充剂显著改善了注意力缺陷多动障碍 (ADHD) 的儿童的执行功能. 这项研究表明,益生菌可能有助于治疗ADHD症状的非药物治疗.
科学领域:
- 神经科学是一个神经科学.
- 儿科 儿科 儿科
- 微生物学 微生物学
背景情况:
- 注意缺陷多动性障碍 (ADHD) 是一种常见的神经发育障碍,影响儿童的学术和社会功能.
- 执行功能对于认知控制至关重要,在患有多动症的儿童中经常受到损害.
研究的目的:
- 研究益生菌补充剂在诊断为ADHD的儿童中增强执行功能的有效性.
- 评估特定益生菌配方对儿童多动症认知表现的影响.
主要方法:
- 一项随机对照试验,涉及84名患有多动症的儿童.
- 参与者每天接受益生菌补充剂 (Lactobacillus Acidophilus,Bifidobacterium Lactis,Bifidobacterium Longum) 或安慰剂两个月.
- 执行功能使用执行功能行为评级目录 (BRIEF) 主表格进行评估,并通过重复测量ANOVA分析数据.
主要成果:
- 在益生菌和安慰剂组之间没有观察到执行功能得分的显著基线差异.
- 益生菌治疗导致执行功能得分明显改善,与安慰剂组相比 (p < 0.001) 在调整混因素后.
- 干预组在治疗后的执行功能障碍得分显著下降.
结论:
- 益生菌补充剂显示出作为一种有益的非药物辅助疗法的潜力,用于改善ADHD儿童的执行功能.
- 建议进行进一步的研究,使用更长的随访期和客观的神经心理评估来证实这些发现.
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