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相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

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生物标志物 生物标志物

Jake A Galler1, Liuqing Yang2, Chao-Yi Wu1

  • 1Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
PubMed
概括

使用游戏数据,MIND GamePack有效地区分了认知正常的个人和认知障碍的人. 这个数字工具对认知评估和跟踪随时间变化的变化充满希望.

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科学领域:

  • 神经科学是一个神经科学.
  • 数字健康数字健康
  • 认知科学 认知科学

背景情况:

  • 传统的神经心理评估在频繁测量和家庭合规性方面面临挑战.
  • 认知障碍者可能会觉得标准评估令人厌烦.
  • 数字化适应通常在可靠性和参与者参与方面扎.

研究的目的:

  • 评估MIND GamePack的有效性,这是一个基于平板电脑的游戏化认知评估工具.
  • 为了确定游戏功能是否可以区分认知正常和受损个体.
  • 通过标准的神经心理测试来验证数字生物标志物.

主要方法:

  • 60名参与者 (认知正常和受损) 在两周内玩了四款iPadOS游戏.
  • 分析了十个游戏特征,以比较认知群体.
  • 斯皮尔曼相关性评估了数字生物标志物和标准测试 (RBANS,TMT) 之间的关系.

主要成果:

  • 十分之九的特征成功地将认知正常与受损参与者区分开来.
  • 游戏功能与记忆,语言和执行功能指标有显著的相关性.
  • 具体来说,百分比准确度与记忆指数相关,硬点数与执行功能测试相关.

结论:

  • 在识别认知状态差异方面,MIND游戏包证明了其有效性.
  • 来自游戏化评估的数字生物标志物可以反映记忆,语言和执行功能.
  • 游戏化评估为临床试验,查和认知健康监测提供了一个有希望的方法.