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Updated: Jan 7, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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药物开发 药物开发

Sergey A Trushin1, Mark Ostroot1, Eugenia Trushina2,3

  • 1Department of Neurology, Mayo Clinic, Rochester, MN, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
PubMed
概括

新的化合物C458和C273弱抑制线粒体复合物I (mtCI),激活神经保护反应. 这种阿尔茨海默病 (AD) 策略增强了线粒体功能和自,显示了疾病修饰的希望.

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