痴呆症护理研究和心理社会因素
Rachel A McCray1, Anthony Q Briggs1, Mark A Bernard1
1NYU Grossman School of Medicine, New York, NY, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
概括
过度白天嗜睡 (EDS) 并没有影响健康老年人的认知表现. 然而,种族影响了认知功能,较高的嗜睡得分与黑人个体的记忆和语言表现差异相关.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 睡眠医学 睡眠医学
背景情况:
- 过度的白天嗜睡 (EDS) 与认知能力下降和阿尔茨海默病风险有关.
- 关于EDS对不同种族和性别群体在不睡觉的老年人影响的研究有限.
研究的目的:
- 调查健康老年人的嗜睡得分和认知表现之间的关联.
- 为了确定这种关联是否因种族和性别而异.
主要方法:
- 对186名认知正常的老年人 (白人和黑人) 的横截面分析.
- 使用爱普沃思睡眠度量 (ESS) 评估睡眠;通过UDS神经心理电池评估认知表现.
- 线性混合效应模型分析了关联,控制了相关的共变量并检查了相互作用效应 (ESS*种族,ESS*性别).
主要成果:
- 在ESS得分和整体认知表现之间没有发现独立的关联.
- 种族与认知表现有关;黑人表现比白人差.
- 性别影响了记忆 (女性更好) 和执行功能 (男性更好) 的表现.
- 种族和ESS在记忆和语言表现上的显著相互作用;更高的嗜睡与黑人个体的表现差相关.
结论:
- 在一个不睡觉,认知健康的队列中,嗜睡得分并没有独立影响认知表现.
- 观察到种族特异性影响,特别是在记忆和语言领域,在那里,更高的嗜睡与黑人参与者的表现较差有关.
- 这些发现表明,睡眠如何影响老年人的认知能力可能存在基于种族的差异.
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