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临床表现临床表现

Jyothi M S Gowda¹, Aparna N P¹, Kavya K Kumar¹

¹National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.

Alzheimer's & dementia : the journal of the Alzheimer's Association

|December 26, 2025

概括

临床痴呆症评级 (CDR) 和印度语精神状态检查 (HMSE) 与认知障碍的临床评估显示中等一致. CDR显示了与临床评估非常好的一致性,而HMSE显示了中度的一致性.

科学领域:

神经学神经学
老年病的医生老年病的医生
精神病学是一个精神病学.

背景情况:

临床痴呆评分 (CDR) 和印度语精神状态检查 (HMSE) 在印度广泛用于评估认知障碍.
CDR评估六个认知领域,而HMSE是印度人口的31点测试.
这项研究调查了CDR,HMSE和专家临床评估 (CE) 之间的诊断一致性.

研究的目的:

评估临床痴呆评分 (CDR),印度语精神状态检查 (HMSE) 和专家临床评估 (CE) 之间的诊断一致性.
建立CDR和HMSE的可靠性,作为印度背景下认知障碍分类的工具.

主要方法:

分析了85名参与者的数据,由专家老年精神病医生的CE作为黄金标准.
临床痴呆症评级 (CDR) 和印度语精神状态检查 (HMSE) 是由训练有素的研究人员进行的.
使用弗莱斯的多级卡帕和科恩的加权卡帕来评估协议.

主要成果:

CDR,HMSE和CE之间的总体一致性是中等的 (Fleiss kappa = 0.556).
CE和CDR之间的协议是"非常好" (加权卡帕 = 0.954),而CE和HMSE之间的协议是"中等" (加权卡帕 = 0.483).
HMSE和CDR之间的协议也"中度" (加权卡帕 = 0.482).

结论:

该研究强调了CDR衍生诊断和基于CE的黄金标准诊断之间的良好一致性.
CDR是分类认知障碍的可靠工具,特别是在印度"大脑年龄差距"的背景下.
此外,HMSE也表现出适度的同意,这表明它在认知评估中的实用性.

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