痴呆症护理研究和心理社会因素
Tara Rak-Areekul1,2, Adipa Chongsuksantikul3, Prawit Oangkhana4
1Division of Neurology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
概括
超过330MET-min/周的体力活动与阿尔茨海默氏症患者更好的认知功能有关.
科学领域:
- 神经学 神经学
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
背景情况:
- 阿尔茨海默病 (AD) 的认知衰退可以通过体力活动来缓解.
- 以前的研究表明,每周330MET-分钟的活动可以改善认知能力.
- 发展中国家的阿尔茨海默病患者的体力活动和认知表现的数据是有限的,他们被诊断为血p-tau 217.
研究的目的:
- 为了研究身体活动水平对AD患者认知表现的影响,AD患者被诊断使用血p-tau 217.7.
- 为了检查330MET-min/wk值是否与这一群体的认知益处有关.
主要方法:
- 通过血p-tau217.7诊断出62名AD患者的横截面分析.
- 使用问卷进行评估的体力活动 (MET-min/wk,IPAQ,AHA).
- 使用MoCA,MMSE,MoCA-MIS和其他神经心理测试评估认知功能;根据混因素进行调整.
主要成果:
- 达到≥330MET-min/周和中度至高IPAQ活动与更好的认知表现相关.
- 总体体力活动与MMSE,MoCA和MoCA-MIS分数积极相关.
- 在对混因素进行调整后,体力活动仍然是认知得分的重要预测因素,包括p-tau 217水平.
结论:
- 身体活动水平≥330MET-min/wk与血p-tau 217.7诊断的阿兹海默症患者的认知能力提高有关.
- 总体身体活动积极影响全球认知功能,独立于混因素.
- 建议促进体育活动作为可修改的干预措施,以减轻AD的认知衰退.
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