1990年至2021年的风湿性心脏病负担:基于2021年全球疾病负担研究的最新分析
Junjie Zhang1,2,3, Ting Ren1, Qiang Zhao1
1Department of Cardiovascular Surgery, Ruijin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in public health
|December 26, 2025
概括
全球努力已经减少了风湿性心脏病 (RHD) 的负担,但显著的差异仍然存在,特别是在低收入国家. 未来的战略必须专注于预防和早期干预服务不足的地区,以打击RHD不平等.
科学领域:
- 心血管流行病学心血管流行病学
- 全球健康差距的差异
- 疾病负担分析疾病负担分析
背景情况:
- 风湿性心脏病 (RHD) 显著影响心血管健康,特别是在低收入和中等收入国家.
- 现有的全球干预措施还没有完全解决与RHD相关的重大负担和不平等问题.
- 这项研究调查了时间趋势,社会经济差异,以及通过社会人口指数 (SDI) 分类的国家对RHD负担的未来预测.
研究的目的:
- 评估全球RHD负担的时间趋势.
- 分析RHD发病率,流行率和死亡率的社会经济差异.
- 预测未来的RHD负担到2050年,分层由SDI.
主要方法:
- 全球疾病负担分析 针对RHD指标的研究数据 (1990-2021年).
- 使用度指数 (CI) 和不平等斜率指数 (SII) 来量化不平等.
- 负担变化的分解分析和未来预测的贝叶斯年龄-时期-队列模型.
主要成果:
- 全球年龄标准化RHD负担下降,在SDI高的国家减少更大.
- 观察到持续的差异,低SDI地区承担的负担不成比例地更高.
- 人口增长和老龄化,而不是流行病学改善,推动了低SDI国家的绝对RHD负担增加.
结论:
- 尽管取得了进展,但在RHD负担方面仍然存在显著的社会经济不平等,并预计将继续存在.
- 未来的RHD控制策略必须优先考虑预防,早期干预和低资源环境中的长期护理.
- 有针对性的干预措施对于解决脆弱人群中持续存在的RHD不平等至关重要.
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