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Updated: Jan 7, 2026

Using the Open-Source MALDI TOF-MS IDBac Pipeline for Analysis of Microbial Protein and Specialized Metabolite Data
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Using the Open-Source MALDI TOF-MS IDBac Pipeline for Analysis of Microbial Protein and Specialized Metabolite Data

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一个快速且具有成本效益的管道,用于从细菌基因组草稿中识别和捕获BGC

Marco A Campos-Magaña1,2, Vitor A P Martins Dos Santos1,3, Luis Garcia-Morales2

  • 1Dept. Bioprocess Engineering, Wageningen University and Research, Wageningen, the Netherlands.

Bio-protocol
|December 26, 2025
PubMed
概括

这项研究介绍了一种具有成本效益的协议,用于使用牛津纳米孔技术测序和生物信息学从土壤细菌中发现新型天然产品. 该方法可以快速识别和克隆大型生物合成基因集群,用于潜在的医学和生物技术应用.

关键词:
这就是反SMASH.生物合成基因集群生物合成基因集群基因组开采是为了挖掘基因组.微生物基因组学 微生物基因组学菌菌菌的存在 菌菌菌的存在牛津纳米孔测序的测序与转变相关的重组克隆.

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Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
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