冷的高级富血小板纤维素作为根覆盖修改道技术的辅助:一个试点随机临床试验
Sruthima N V S Gottumukkala1, Murali Krishna1, Gautami S Penmetsa1
1Department of Periodontics and Implantology, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.
Journal of Indian Society of Periodontology
|December 26, 2025
概括
与新鲜的PRF相比,冷的高级富血小板纤维素 (PRF) 在治疗多个相邻的衰退缺陷方面表现出优越的根覆盖和机械性能. 这种冷的PRF可能为牙衰退治疗提供一种有效的替代方案.
科学领域:
- 牙周再生 牙周再生
- 牙科中的生物材料.
背景情况:
- 富含血小板纤维素 (PRF) 是第二代血液缩剂,用于牙周再生.
- 现有的PRF方法有局限性,包括膜脆弱性和不可预测的结果.
- 研究了冷的高级PRF (-24小时-20°C),以改善处理和有效性.
研究的目的:
- 为了评估冷高级PRF (Fz-PRF) 与新鲜高级PRF (A-PRF) 的临床结果,使用修改冠状腺高级道 (MCAT) 技术.
- 评估根覆盖,机械特性,术后愈合,以及患者对治疗多重相邻衰退缺陷 (MARDs) 的满意度.
主要方法:
- 潜在的,分口,随机对照临床试验,有10名参与者和42颗牙.
- 双边MARD患者通过MCAT接受Fz-PRF或A-PRF治疗.
- 衰退深度/宽度的评估,完整的根覆盖率,%RC,机械特性,愈合指数和患者报告的结果.
主要成果:
- 冷PRF组显著表现出更好的%RC (P=0.025),RW (P=0.044),机械特性 (P=0.000) 和美学满意度 (P=0.015).
- 两组之间没有注意到患者不适或术后愈合的显著差异.
- Fz-PRF表现出优越的针通道易度,手术处理和减少膜磨损.
结论:
- 与新鲜PRF相比,冷的高级PRF表现出优越的根覆盖,机械性能和美观结果.
- Fz-PRF可以作为治疗牙衰退的有效替代品.
- 结合Fz-PRF的MCAT技术显示出对管理MARDs的承诺.
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