疫情前的大脑结构和COVID-19恐惧:对创伤后压力和一般痛苦的洞察力
Ting Zhang1, Dongmei Wu2, Yixun Tang3
1Department of Health Humanities Research Center, Sichuan Vocational College of Health and Rehabilitation, Zigong, Sichuan, China.
Frontiers in psychiatry
|December 26, 2025
概括
疫情前的灰色物质量预测了对COVID-19的恐惧,然后预测了长期的PTSD症状和一般的痛苦. 这突出了岛屿在流行病期间恐惧反应和心理结果中的作用.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 公共卫生 公共卫生
背景情况:
- 恐惧反应与各种大脑区域有关.
- 之前关于COVID-19恐惧和神经连接的研究发现,大流行前大脑结构的作用存在差距.
- 了解COVID-19恐惧的神经生物学基础对于预测长期心理影响至关重要.
研究的目的:
- 调查COVID-19恐惧中的个人差异的神经结构基础.
- 探索疫情前大脑结构如何影响COVID-19爆发期间的恐惧.
- 检查神经行为机制,将COVID-19恐惧与后来的PTSD症状和一般痛苦联系起来.
主要方法:
- 一项涉及中国115名大学生的前性纵向研究.
- 采集了使用3.0TMRI的流行前大脑结构数据.
- 在疫情高峰期间评估COVID-19恐惧和一年后的PTSD/痛苦,使用结构方程建模进行分析.
主要成果:
- 基线灰色物质体积 (GMV) 在左侧和右侧胰岛素与COVID-19恐惧正相关.
- 调解分析表明,COVID-19恐惧调解了双边岛屿GMV对随后的PTSD症状和一般痛苦的影响.
结论:
- 双边岛屿GMV是传染病爆发期间恐惧的关键预测因素.
- 恐惧在岛屿结构和未来的心理问题之间起到调解作用.
- 调查结果可以帮助识别易受伤害的群体,并在疫情期间提供有针对性的心理健康干预措施.
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