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Updated: May 12, 2026

Generation of Subcutaneous and Intrahepatic Human Hepatocellular Carcinoma Xenografts in Immunodeficient Mice
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HMGCR:恶性瘤中心 - 癌症诊断和治疗的前沿领域

Yisong Yang1, Yiting Liu1, Teng Zou1

  • 1Engineering Technology Research Center for Functional Component Utilization of Organic Natural Products, Medical College, Dalian University, Dalian, Liaoning, China.

Frontiers in oncology
|December 26, 2025
PubMed
概括

胆固醇合成酶HMG-CoA减少酶 (HMGCR) 驱动瘤生长和免疫逃避. 准HMGCR-TNF-α轴为增强癌症治疗提供了一种新的策略.

关键词:
在HMGCR中,HMGCR是最重要的.这就是TNF-α.胆固醇的代谢 胆固醇的代谢信号通道的信号路径.瘤微环境是一个微环境.

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