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循环PD-1效应记忆T细胞预测了在晚期胃癌中抗PD-1的疗效

Kongcheng Wang1,2, Jie Shao1,2, Kai Xin1,2

  • 1Department of Oncology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

Frontiers in immunology
|December 26, 2025
PubMed
概括

高编程细胞死亡-1 (PD-1) 表达在效应器记忆T细胞上预测胃癌患者对化疗免疫治疗的反应更好. 这一发现可能有助于确定那些将受益于PD-1阻断治疗的患者.

关键词:
在PD-1中使用PD-1.生物标志物生物标志物效应器记忆T细胞是T细胞.胃癌 胃癌 是一种胃癌.免疫疗法 免疫疗法周围血液 周围血液

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The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
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