与腹部恶性瘤伪装的IgG4相关疾病:一个诊断挑战
Zahra F Rahmatullah1, Ralph H Hruban2, Elliot K Fishman1
1Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD, 21287, USA.
Radiology case reports
|December 26, 2025
概括
本病例报告详细介绍了一种罕见的IgG4相关疾病 (IgG4-RD) 呈现,模仿年轻男性小肠癌. 准确的诊断需要彻底的调查超出初始成像,强调IgG4-RDD.
科学领域:
- 免疫学 免疫学 免疫学
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
背景情况:
- 免疫球蛋白G4相关疾病 (IgG4-RD) 是一种复杂的纤维炎性自身免疫性疾病.
- 它的病理生理学仍然不完全理解,影响多个器官具有特征性炎症,纤维化和IgG4阳性血细胞透.
- IgG4-RD可以呈现出质量形成的病变,通常模仿恶性瘤.
研究的目的:
- 报告一种罕见且不典型的IgG4相关疾病 (IgG4-RD) 病例,呈现为终端质质.
- 要突出IgG4-RD在模仿胃肠道恶性瘤时所带来的诊断挑战.
- 强调全面诊断评估对于准确的IgG4-RD诊断和管理的重要性.
主要方法:
- 一个年轻男性的病例报告,患有腹部疼痛和明显的膨胀.
- 利用成像研究,包括腹部CT,以评估终端质和淋巴腺病变.
- 进行了结肠镜检查和活检,以确定他的病理学诊断.
主要成果:
- 图像检查显示,有临终性质质量与淋巴腺病变,最初怀疑是小肠癌.
- 通过结肠镜和活检进行的组织病理学检查证实了IgG4相关疾病的诊断.
- 这一案例凸显了IgG4-RD模仿恶性瘤的潜力.
结论:
- 与IgG4相关的疾病可以异常呈现,模仿小肠癌等严重疾病.
- 彻底的诊断工作,包括组织病理学,对于区分IgG4-RD和恶性瘤至关重要.
- 准确的诊断对于适当的患者管理和IgG4-RD治疗至关重要.
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