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Updated: Jan 7, 2026

Differentiation of Functional Osteoclasts from Human Peripheral Blood CD14+ Monocytes
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Differentiation of Functional Osteoclasts from Human Peripheral Blood CD14+ Monocytes

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在纤维细胞样同胞细胞中,TNF诱导的神经平素-2会加剧类风湿性关节炎

Ke Jin1,2, Jingjing Ran1,2, Yuxin Deng1,2

  • 1Department of Rheumatology and Immunology, and Laboratory of Human Diseases and Immunotherapies, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan Province, China.

Arthritis & rheumatology (Hoboken, N.J.)
|December 26, 2025
PubMed
概括

瘤坏死因子 (TNF) 诱导的神经素-2 (NRP2) 驱动类风湿性关节炎 (RA) 炎症和疾病进展. 针对纤维细胞样同胞细胞 (FLS) 中的TNF-p65-NRP2通路,为RA提供了一种新的治疗策略.

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