痴呆症护理研究和心理社会因素
Elisabeth Wood1, Meron Azage1, Laynie Dratch1
1University of Pennsylvania, Philadelphia, PA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
概括
一个聊天机器人有效地教育患者APOE基因型和阿尔茨海默病 (AD) 测试对抗粉样蛋白抗体疗法 (AAT). 所有基因型的高参与度表明患者对遗传信息和支持感兴趣.
科学领域:
- 神经学 神经学
- 遗传学 遗传学 是一个
- 数字健康数字健康
背景情况:
- 对于那些考虑使用抗粉样抗体疗法 (AAT) 的患者来说,APOE基因定型至关重要.
- 对阿尔茨海默病 (AD) 的遗传检测需要遗传咨询,因为它具有复杂的含义.
- 对AD遗传测试和咨询的需求增加,需要像数字工具这样的创新解决方案.
研究的目的:
- 评估定制聊天机器人的实用性,以教育患者AD和APOE遗传学.
- 评估患者与遗传信息和咨询请求的数字工具的接触.
- 改善在AAT的背景下提供遗传教育和支持.
主要方法:
- 开发了一个定制的聊天机器人,提供关于AD和APOE遗传学的教育内容.
- 聊天机器人提供了请求遗传咨询师协助的选项.
- 收集和分析了患者参与数据和退出访谈反.
主要成果:
- 聊天机器人向369名患者推出,其中54.5%的人参与.
- 45.7%的参与用户访问了教育内容;7%要求进一步的遗传咨询.
- 参与和内容访问显示了APOE基因型 (e4同胞体,异胞体,非载体) 的变化.
结论:
- 基于聊天机器人的APOE教育是有效的,并得到了接受AAT测试的患者的好评.
- 患者反强调了数字工具在遗传教育和支持方面的价值.
- 聊天机器人是提供遗传教育和促进在AD护理中获得遗传咨询的可行选择.
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