临床表现 临床表现
Justina P Tavana1, John Kauwe1, JoAnn T Tschanz2
1Brigham Young University, Provo, UT, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
概括
对萨摩亚和加人群的文化适应的认知评估得到了验证. 这些工具有助于在不同社区早期发现和诊断阿尔茨海默病和相关痴呆症 (ADRD).
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
背景情况:
- 认知健康评估和痴呆症研究需要文化和语言多样化的工具.
- 阿尔茨海默病和相关痴呆症 (ADRD) 影响着全球多样化的人口.
- 太平洋岛民,包括萨摩亚人和通加人,由于不同的文化和语言特征,需要量身定制的认知评估工具.
研究的目的:
- 为了验证萨摩亚语和通加语版本的AD8和CDR认知查工具.
- 为萨摩亚和加社区确保文化上适当和准确的认知评估.
- 为少数群体解决痴呆症研究的差距.
主要方法:
- 招募了来自散居社区的26名萨摩亚和加参与者 (≥50岁).
- 雇佣双语面试人员进行数据收集和认知评估.
- 利用严格的翻译,逆向翻译,专家审查和重点小组反进行验证.
主要成果:
- 验证的萨摩亚语 (AD8-SMN,CDR-SMN) 和通加语 (AD8-TNG,CDR-TNG) 版本的AD8和CDR.
- 对于AD8 (完美的协议) 和CDR (强大的协议) 证明了强大的互评级可靠性.
- 展示了强大的心理测量特性,在萨摩亚语和通加语评估和MoCA之间存在显著的相关性.
结论:
- 验证的萨摩亚和通加AD8和CDR工具为早期ADRD检测和诊断提供了可靠的手段.
- 这些工具解决了对少数群体文化相适应的痴呆症研究工具的关键需求.
- 经验证的工具有助于改善认知健康结果,并确保公平的痴呆症护理.
相关概念视频
Chronic Kidney Disease II: Clinical Manifestations
520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations
299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis
364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations
436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management
652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies
437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437


