临床表现 临床表现
Davina Kavita Premraj1, Yasmin Soliman2, Carmela Tartaglia3
1Krembil Discovery Tower, Tanz Centre for Neurodegenerative Disease, Concussion and Memory Clinic, Toronto, ON, Canada.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
概括
老年女性比男性表现出更持久的脑震荡症状,痴呆症在65岁以上的人群中更为常见. 需要进一步的研究来了解脑震荡.
科学领域:
- 神经学 神经学
- 老年学是一门学科.
- 认知科学 认知科学
背景情况:
- 跌倒和脑震荡在老年人群中越来越令人担忧.
- 脑震荡的老年人经常被误诊为轻度认知障碍 (MCI) 或痴呆症.
- 脑震荡后认知表现的性别差异需要进一步调查.
研究的目的:
- 为了研究老年人脑震荡后认知表现的性别差异.
- 为了分析正常认知,MCI和老年人脑震荡后痴呆症的患病率.
- 为了确定脑震荡结果中的潜在基于性别的差异.
主要方法:
- 在多伦多西部医院 (过去3年) 对50岁以上脑震荡患者的回顾性研究.
- 通过REDCap收集的数据,包括人口统计,诊断和多伦多认知评估 (TorCA).
- 根据TorCA得分,MCI概率和年龄,根据性别和认知状态 (正常,MCI,痴呆症) 分类的患者.
主要成果:
- 更多的女性 (n=50) 比男性 (n=26) 在三年内出现脑震荡.
- 与男性 (21%) 相比,较少的女性 (6%) 患有MCI,尽管在统计学上不显著 (p=0.12).
- 痴呆的患病率在性别之间相似 (35%的女性,38%的男性),65岁以上的成年人 (48.15%) 的患病率更高.
结论:
- 在老年人中,女性表现出持续性脑震荡症状的患病率高于男性.
- 与年轻人 (50-64岁) 相比,老年人 (65岁以上) 患痴呆症的频率更高.
- 需要进一步的研究来澄清脑震荡在MCI和痴呆症诊断中的作用.
相关概念视频
Chronic Kidney Disease II: Clinical Manifestations
520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations
299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis
364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations
436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management
652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies
437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437


