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Updated: Jan 7, 2026

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在深度大脑刺激后,单源LRRK2帕金森病的运动反应:系统性审查和元分析

M Ar Rochmah1,2,3, S Subagya4,2, S Wibowo4,2

  • 1Department of Neurology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia. mawaddah_ar@ugm.ac.id.

The Medical journal of Malaysia
|December 26, 2025
PubMed
概括

帕金森病 (PD) 患者的深度大脑刺激 (DBS) 结果与富含白氨酸的重复激酶2 (LRRK2) 突变因遗传变异而异. 与R1441G不同的是,LRRK2-G2019S和LRRK2-G2385R突变在DBS后显示出改善的运动功能.

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