临床表现 临床表现
Latha Velayudhan1, Maahek Kapasi1, Ellie Pickering2
1Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
概括
两年后,有或没有COVID-19相关的嗅觉丧失的老年人表现出类似的嗅觉识别测试成绩. 这表明,感染后组之间嗅觉功能没有显著差异.
科学领域:
- 老年学是指老年学的学科.
- 传染性疾病 传染性疾病
- 神经学 神经学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 是一种全球性流行病,常见症状是嗅觉功能障碍.
- 嗅觉障碍与不良健康结果有关,包括死亡率,生活质量降低,抑郁症和痴呆风险.
- 老年人中COVID-19相关的嗅觉功能障碍的影响需要进一步调查.
研究的目的:
- 评估COVID-19感染后老年人 (50岁以上) 的嗅觉识别缺陷.
- 为了比较COVID-19后有或没有自我报告的气味问题的老年人中的嗅觉功能.
主要方法:
- 进行了一项纵向在线调查 (Covid-19流行病中老年人嗅觉和味觉功能 - STAP).
- 参与者 (n=150,年龄和性别匹配) 完成了宾夕法尼亚大学气味识别测试 (UPSIT) 套件.
- 收集的数据包括COVID-19症状,自我报告的认知问题和社会人口统计细节.
主要成果:
- 在有或没有COVID-19后气味丧失的老年人之间,在UPSIT总得分中没有发现显著差异 (p=0.555).
- 在UPSIT中,女性得分高于男性 (p=0.002).
- 进一步的分析将探索与认知和其他因素的关联.
结论:
- 患有和没有COVID-19相关的嗅觉功能障碍的老年人在感染后两年表现出类似的嗅觉识别能力.
- 这表明两组之间嗅觉识别功能没有明显的差异.
- 用更大的队列进行纵向研究是必要的,以了解嗅觉障碍和认知风险的轨迹.
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