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临床表现 临床表现

Olufisayo Oluyinka Elugbadebo1,2, Gabriel O Ogunde3, Joshua O Akinyemi4

  • 1University College Hospital, Ibadan, Oyo, Nigeria.

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概括
此摘要是机器生成的。

痴呆症的行为和心理症状 (BPSD) 与非洲人口的痴呆症严重程度和记忆力下降有关. 有针对性的BPSD管理对于改善低收入和中等收入国家患者护理至关重要.

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科学领域:

  • 神经科学是一个神经科学.
  • 老年学是指老年学的学科.
  • 精神病学是一个精神病学.

背景情况:

  • 痴呆症的行为和心理症状 (BPSD) 在痴呆症患者中很普遍,影响疾病的严重程度和护理人员的福祉.
  • BPSD经常促使低收入和中等收入国家 (LMICs) 的家庭寻求痴呆症的医疗帮助.
  • 在非洲人群中,BPSD,痴呆症严重程度和认知领域之间的关系尚未得到充分研究.

研究的目的:

  • 调查BPSD在患有痴呆症的非洲土著人中的患病率.
  • 检查BPSD和痴呆症严重程度之间的关联.
  • 探索BPSD与该人群中的特定认知领域之间的关系.

主要方法:

  • 一项涉及9个非洲国家的641名参与者的横截面研究 (READD-ADSP项目).
  • 数据采集使用统一数据集 (UDS),神经精神病 inventory问卷 (NPI-Q) 的BPSD,和临床痴呆症评级 (CDR) 的痴呆症严重程度的尺度.
  • 统计分析包括描述性统计,斯皮尔曼的等级相关性和等级线性模型.

主要成果:

  • 漠不关心,兴奋/侵略和抑郁是最常见的BPSD.
  • 在NPI-Q严重性得分和CDR得分之间发现了一个微弱但显著的积极关联 (rho=0.264,p<0.001).
  • 行为症状与痴呆症的严重程度和记忆功能 (数字跨度向后) 有着显著的关联.

结论:

  • BPSD表明并导致痴呆症的严重程度,特别是影响记忆力.
  • 需要针对BPSD进行有针对性的管理,以加强LMIC患者的护理.
  • 进一步的研究是有必要的,以了解在不同非洲人群中BPSD的细微差别.