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Updated: Jan 7, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
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罕见和新型RELA变种有助于系统性自身免疫

Morgan B Downes1, Sonia B Nambadan1, Joanne Chow1

  • 1Division of Immunology and Infectious Diseases, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia.

Arthritis & rheumatology (Hoboken, N.J.)
|December 26, 2025
PubMed
概括

RELA基因的罕见突变会影响自身免疫性疾病中的免疫信号. 一些RELA变异破坏NF-κB活性并改变干扰素信号传递,有助于疾病多样性.

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