临床表现 临床表现
Annie Ching1, Anson Wong2, Bora Nam1
1University of California San Francisco School of Nursing, San Francisco, CA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
概括
该ARISE试点研究表明,社区伙伴关系是招募各种亚裔美国老人的关键,用于阿尔茨海默病和相关痴呆症 (ADRD) 研究. 文化敏感的方法可以改善代表性不足的群体的参与和数据收集.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 社会学 社会学 社会学
背景情况:
- 歧视与阿尔茨海默病和相关痴呆症 (ADRD) 风险有关.
- 这种关联在亚裔美国人中没有得到充分研究,特别是在反亚裔情绪上升的情况下.
- 在ARISE试点研究中,通过检查歧视对特定亚裔美国社区ADRD风险的影响来解决这一差距.
研究的目的:
- 探索经历歧视与中国,韩国和越南语老年人ADRD风险之间的关联.
- 评估招募这些人群进行认知测试和生物样本采集的可行性.
- 突出文化和语言方面的考虑,这对于涉及不同族群的ADRD研究至关重要.
主要方法:
- 参与者以他们的母语进行评估,包括为生物标志物抽取血液和面试,涵盖认知功能,健康和歧视经历.
- 经过验证的工具是根据世卫组织的指导方针采购或翻译/调整的,审查人员接受了文化适当性培训.
- 招聘策略与社区组织共同开发,调整程序并提供文化相关的激励措施,以建立信任并鼓励参与.
主要成果:
- 截至2025年1月23日,ARISE试点研究成功招募了252名参与者 (112名越南人,56名韩国人,84名中国人).
- 217名参与者完成了抽血和采访,证明了研究程序的可行性.
- 量身定制的招聘,社区合作和文化敏感的方法培养了信任,社区和保留.
结论:
- 与社区合作伙伴的合作对于成功招募和完成ARISE试点研究至关重要.
- 这项研究证明了在ADRD研究中进行认知评估和从老年亚裔美国人中收集生物样本的可行性.
- 未来的研究结果将为代表性不足的人群的ADRD研究策略提供信息,强调文化和语言适应.
相关概念视频
Chronic Kidney Disease II: Clinical Manifestations
520
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
520
Coronary Artery Disease III: Clinical Manifestations
299
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
299
Endocarditis II: Clinical Features of Infective Endocarditis
364
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
364
Heart Failure III: Clinical Manifestations
436
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
436
Gastroesophageal Reflux Disease II: Clinical Features and Management
652
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
652
Hypertension III: Clinical Manifestations and Diagnostic Studies
437
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
437


