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临床表现 临床表现

Victória Tizeli Souza1, Barbara Loeblein Uebel2, Gabriela Raquel Paz Rivas3

  • 1Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.

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概括
此摘要是机器生成的。

轻度行为障碍检查清单 (MBI-C) 有效地识别了主观认知衰退 (SCD) 和轻度认知障碍 (MCI) 患者的神经心理症状. MBI-C得分与焦虑,抑郁和认知衰退指标相关,突出其临床相关性.

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科学领域:

  • 神经科学是一个神经科学.
  • 老年学是一门学科.
  • 精神病学是一个精神病学.

背景情况:

  • 轻度行为障碍 (MBI) 涉及神经精神症状,可能是神经退行性疾病的前身.
  • 巴西人患有认知投诉的MBI研究是有限的.
  • 这项研究评估了MBI-检查表 (MBI-C) 在一个巴西队列的主观认知衰退 (SCD) 和轻度认知障碍 (MCI).

研究的目的:

  • 评估MBI-Checklist (MBI-C) 在SCD和MCI患者中识别神经精神症状的实用性.
  • 探索MBI-C得分与其他认知和心理健康指标之间的相关性.
  • 确定MBI-C在巴西人口的行为评估中的相关性.

主要方法:

  • 该研究分析了来自巴西主观认知衰退 (BRASCODE) 队列的数据,包括完成了12个月随访的参与者.
  • 参与者进行了评估,包括MBI-Checklist (MBI-C),Memory Complaint Scale (MCS),神经精神病 inventory-Questionnaire (NPI-Q),老年抑郁量表 (GDS),老年焦虑量表 (GAI),迷你精神状态检查 (MMSE) 和临床痴呆评分 (CDR).
  • 进行了相关性分析,以检查各种临床和人口统计变量之间的关系,显著性水平设置为p < 0.05.

主要成果:

  • MBI-C参与者得分与抑郁症 (GDS) 和焦虑症 (GAI) 症状正相关.
  • MBI-C 告知者得分与 NPI-Q 和告知者报告的认知衰退 (CDR-SOB) 有很强的相关性.
  • 参与者MBI-C得分与正规教育呈现负相关性;参与者和告知者MBI-C得分之间没有发现显著的相关性.

结论:

  • MBI-C有效地检测SCD和MCI患者的神经精神症状.
  • MBI-C得分,特别是基于信息者的得分,与焦虑,抑郁和认知障碍指标有显著的相关性.
  • 建议对更大样本进行进一步的研究,以充分了解MBI与这些人群认知衰退的关联.