阿姆斯特丹多民族儿童食物过敏增长不佳
A M Mooij-Nieberg1, N A Ten Hoope1, O van Doorn1
1Department of Pediatrics, OLVG Hospital, Amsterdam, The Netherlands.
概括
与生长参考相比,食物过敏 (FA) 儿童的体重和BMI Z-分数较低. 增长迟缓,特别是长度,发生在这些孩子的早期生活.
科学领域:
- 儿童营养学 儿童营养学
- 过敏和免疫学 过敏和免疫学
背景情况:
- 食物过敏 (FA) 与儿童的生长迟缓有关.
- 潜在的原因包括营养缺乏和潜在的疾病机制.
研究的目的:
- 评估荷兰儿童患有FA的生长参数 (身高相应年龄Z分数 (HAZ),体重相应年龄Z分数 (WAZ),BMI相应年龄Z分数 (BAZ))
- 为了确定这个人口中增长的预测因素.
主要方法:
- 这是一项单一中心对114名患有FA的儿童 (0,5-18岁) 的研究.
- 使用增长分析仪和世卫组织软件计算的Z分数,与荷兰参考数据进行比较.
- 多变量线性回归和线性混合模型分析了预测因素和增长轨迹.
主要成果:
- 在6.1%的儿童中观察到衰退 (HAZ <-2),高于预期的2.5%.
- 分别有28.1%和29.2%的HAZ和WAZ<-1,超过预期的15.9%.
- 喘和非IgE介导的牛奶过敏 (CMA) 与较低的WAZ和BMI相关;长度从5-11个月恶化,在三岁左右稳定.
结论:
- 患有FA的儿童,特别是患有喘和非IgE介导的CMA的儿童,体重和BMI Z-分数较低.
- 在婴儿期早期观察到长度,在三岁左右稳定.
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