益生菌作为微塑料诱导毒性的调节剂:系统性审查
Mahdi Adabi1, Ahmad Reza Dehpour2, Hamed Shafaroodi2
1Department Medical Nanotechnology , School of Advanced Technologies in Medicine Tehran University of Medical Sciences, Tehran, Iran.
Probiotics and antimicrobial proteins
|December 26, 2025
概括
微塑料是广泛存在的环境污染物. 这次审查发现,益生菌,特别是乳酸菌种,可以通过减轻氧化应激减轻微塑料毒性.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 毒理学 毒理学 毒理学
背景情况:
- 微塑料是普遍存在的环境污染物,人类不可避免地接触到它们.
- 微塑料的有毒影响需要减少负担的策略.
- 益生菌因其健康益处和减轻污染物毒性的潜力而越来越受认可.
研究的目的:
- 系统地审查益生菌在减少微塑料诱导的毒性方面的潜力.
- 阐明益生菌对微塑料产生保护作用的作用机制.
- 确定常用的益生菌物种及其在管理微塑料暴露中的有效性.
主要方法:
- 在PubMed,Scopus和Web of Science进行了全面的系统文献搜索,没有时间限制.
- 关键词被精心设计,以捕捉有关微塑料和益生菌的相关研究.
- 一个严格的评估过程涉及到初级和二级选,有15个选定的手稿 (3 in vitro,12 in vivo) 用于数据提取.
主要成果:
- 在针对微塑性毒性的研究中,乳酸菌种被确定为最常用的益生菌.
- 鉴定出益生菌的主要保护机制是减少微塑料暴露引起的氧化应激.
- 来自体外和体内研究的证据支持益生菌在改善微塑料相关伤害方面的作用.
结论:
- 益生菌,特别是乳酸菌种,在抵消微塑料毒性方面显示出显著的潜力.
- 减少氧化应激是益生菌提供对微塑料保护的关键机制.
- 进一步研究和应用益生菌可能是管理与微塑料污染相关的健康风险的可行策略.
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