Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

High-Resolution Mass Spectrometry (HRMS)01:15

High-Resolution Mass Spectrometry (HRMS)

2.3K
The resolution of a mass spectrometer depends on the efficiency of separating ions with different ion masses. The mass of an atom is approximated to the sum of the masses of protons and neutrons inside, considering the masses of protons and neutrons as equal. However, the masses of the proton (1.6726 × 10−24 g) and neutron (1.6749 × 10−24 g) are not truly equal. There is a minor error in the expression of atomic masses relative to the simplest atom of hydrogen. For...
2.3K
NMR Spectrometers: Resolution and Error Correction01:14

NMR Spectrometers: Resolution and Error Correction

1.0K
When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
1.0K
Propagation of Uncertainty from Systematic Error01:10

Propagation of Uncertainty from Systematic Error

1.2K
The atomic mass of an element varies due to the relative ratio of its isotopes. A sample's relative proportion of oxygen isotopes influences its average atomic mass. For instance, if we were to measure the atomic mass of oxygen from a sample, the mass would be a weighted average of the isotopic masses of oxygen in that sample. Since a single sample is not likely to perfectly reflect the true atomic mass of oxygen for all the molecules of oxygen on Earth, the mass we obtain from this...
1.2K
Conservation of Mass in Finite Cotrol Volume01:16

Conservation of Mass in Finite Cotrol Volume

1.7K
The principle of conservation of mass is a fundamental law in fluid mechanics and is applied using the continuity equation. We apply the concept to a finite control volume to derive the continuity equation.
A system is defined as a collection of unchanging contents, and the conservation of mass states that a system's mass is constant.
1.7K
Conservation of Mass in Fixed, Nondeforming Control Volume01:07

Conservation of Mass in Fixed, Nondeforming Control Volume

1.6K
The principle of conservation of mass is fundamental in fluid dynamics and is crucial for analyzing flow within fixed control volumes, such as pipes or ducts. This principle states that the total mass within a control volume remains constant unless altered by the inflow or outflow of mass through the control surfaces. This results in a vital relationship for steady, incompressible flow where the mass entering a system equals the mass leaving it.
In the case of a sewer pipe, which can be modeled...
1.6K
Reduced Mass Coordinates: Isolated Two-body Problem01:12

Reduced Mass Coordinates: Isolated Two-body Problem

2.3K
In classical mechanics, the two-body problem is one of the fundamental problems describing the motion of two interacting bodies under gravity or any other central force. When considering the motion of two bodies, one of the most important concepts is the reduced mass coordinates, a quantity that allows the two-body problem to be solved like a single-body problem. In these circumstances, it is assumed that a single body with reduced mass revolves around another body fixed in a position with an...
2.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Is <i>Hydra</i> Axis Definition a Fluctuation-Based Process Picking Up External Cues?

Journal of developmental biology·2025
Same author

Mechanochemical patterning localizes the organizer of a luminal epithelium.

Science advances·2025
Same author

The Nature of the Spark Is a Pivotal Element in the Design of a Miller-Urey Experiment.

Life (Basel, Switzerland)·2023
Same author

3D single cell migration driven by temporal correlation between oscillating force dipoles.

eLife·2022
Same author

Photoactivation of Cell-Free Expressed Archaerhodopsin-3 in a Model Cell Membrane.

International journal of molecular sciences·2021
Same author

A Methylation-Directed, Synthetic Pap Switch Based on Self-Complementary Regulatory DNA Reconstituted in an All <i>E. coli</i> Cell-Free Expression System.

ACS synthetic biology·2021

相关实验视频

Updated: Jan 7, 2026

Setting Limits on Supersymmetry Using Simplified Models
07:46

Setting Limits on Supersymmetry Using Simplified Models

Published on: November 15, 2013

8.9K

UHRMS公式赋值:基于二奥芬丁的重新校准产生了洛伦兹质量误差分布作为限制因素.

Neda Safaridehkohneh1, Albrecht Ott1

  • 1Department of Physics, Center for Biophysics, Saarland University, Saarbrücken 66123, Germany.

Journal of the American Society for Mass Spectrometry
|December 26, 2025
PubMed
概括

本研究介绍了Diophantine方法用于超高分辨率质谱学 (UHRMS) 中的分子公式分配. 这种新的方法通过统计分析质量错误来提高复杂样本的光谱解释精度.

科学领域:

  • 分析化学 分析化学
  • 频谱测量是一种光谱测量.
  • 计算化学计算化学

背景情况:

  • 超高分辨率质谱 (UHRMS) 对于分析复杂分子混合物至关重要.
  • 富里埃转换技术 (FTICR-MS,FT-Orbitrap-MS) 提供了高分辨率,但也带来了解释方面的挑战.
  • 复杂样品的非目标分析往往导致难以进行光谱解释.

研究的目的:

  • 在UHRMS中引入一种新的迪奥芬丁方法,用于在UHRMS中准确的分子公式分配.
  • 为了解决复杂样品的光谱解释方面的挑战.
  • 提高分子公式确定的统计一致性和准确性.

主要方法:

  • 开发和应用一个Diophantine方法用于分子公式赋值.
  • 使用高斯分布对随机质量误差的统计分析.
  • 区分系统的校准错误和随机的质量错误.
  • 随机质量误差作为洛伦兹分布的量化.

主要成果:

  • 狄奥芬丁方法使得统计学上一致的分子公式分配成为可能.
  • 来自低于最佳校准的系统错误可以有效地与随机错误区分开来.
  • 该方法量化了随机质量误差,与基于富里埃变换的仪器一致.

更多相关视频

Calibration Procedures for Orthogonal Superposition Rheology
08:43

Calibration Procedures for Orthogonal Superposition Rheology

Published on: November 18, 2020

2.3K
Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
08:40

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

Published on: January 20, 2022

4.8K

相关实验视频

Last Updated: Jan 7, 2026

Setting Limits on Supersymmetry Using Simplified Models
07:46

Setting Limits on Supersymmetry Using Simplified Models

Published on: November 15, 2013

8.9K
Calibration Procedures for Orthogonal Superposition Rheology
08:43

Calibration Procedures for Orthogonal Superposition Rheology

Published on: November 18, 2020

2.3K
Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
08:40

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

Published on: January 20, 2022

4.8K
  • 分子公式分配接近可实现准确性的理论极限.
  • 结论:

    • 狄奥芬丁法为UHRMS中的分子公式分配提供了一个强大的方法.
    • 这种方法显著提高了复杂样品的光谱解释精度.
    • 该技术是自相一致的,并推动了质谱学精度的界限.