痴呆症护理研究和心理社会因素
Joey A Contreras1, Nancy E Ortega2, Humberto Parada3
1Alzheimer's Disease Cooperative Study (ADCS), University of California, San Diego, La Jolla, CA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
概括
每天的歧视可能会对墨西哥裔美国成年人的认知功能产生负面影响,而不依赖于遗传因素. 这突显了社会决定因素在该人口痴呆风险中的作用.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 社会学 社会学 社会学
背景情况:
- 健康的社会决定因素,如歧视,可能会增加墨西哥裔美国人 (MA) 的痴呆风险,超出遗传因素 (APOE4).
- 鉴于拉丁裔人口中痴呆风险较高,调查歧视对认知健康的影响至关重要.
研究的目的:
- 检查MA和非西班牙裔白人 (NHW) 成年人感知到的日常歧视和认知功能之间的关联.
- 在分析中调整遗传风险因素 (APOE4) 和人口变量.
主要方法:
- 利用了来自健康和衰老大脑研究-健康差异 (HABS-HD) 的基线数据.
- 通过西班牙语-英语口头学习测试 (SEVLT) 评估认知功能,并通过日常歧视量表 (EDS) 进行歧视.
- 使用多变量线性回归,控制年龄,性别,教育和APOE4.4.
主要成果:
- 在总样本 (p=0.27) 中,没有发现感知歧视与SEVLT分数之间的显著关联.
- 在MA参与者中,更高的歧视感与较低的SEVLT分数相关 (p=0.03).
- 在NHW参与者中,没有观察到歧视和SEVLT得分之间的显著关联 (p=0.32).
结论:
- 感知到的日常歧视可以预测MA成年人的认知功能.
- 社会和社会互动可以不成比例地影响特定人群的认知健康.
- 进一步的研究应该探索歧视如何影响高负担人群中阿尔茨海默病的病理学.
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