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Updated: Jan 7, 2026

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在跨性别成年人中,丸激素治疗对细胞染色体P450 3A和P-糖蛋白活性使用米达佐拉姆和迪戈辛作为探针基质的影响

Michiko Hunter1, Rene Coig1, Linda Risler1

  • 1Department of Pharmacy, University of Washington, Seattle, Washington, USA.

Pharmacotherapy
|December 26, 2025
PubMed
概括

确认性别的丸激素治疗并没有显著改变由CYP3A酶或P-糖蛋白运输的药物代谢. 这表明通过这些途径处理的药物的药理动力学的影响最小,尽管建议对治疗指数狭窄的药物保持谨慎.

关键词:
在CYP3A.这是一种P-glycoprotein蛋白.药物动力学 药物动力学测试剂 测试剂 测试剂 测试剂变性人 变性人 变性人

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