Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

516
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A DERIVED RELAXATION CONTRAST FROM SYNTHETIC MRI FOR DETECTING NETWORK MICROSTRUCTURAL VULNERABILITY.

bioRxiv : the preprint server for biology·2026
Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Alzheimer's Imaging Consortium.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Olfactory Network Functional Connectivity as a Marker for Parkinson's Disease Severity.

Life (Basel, Switzerland)·2025
Same author

Linking genetics to MRI-DTI: <i>HFE</i> polymorphism delays Alzheimer's disease white matter degeneration in <i>APOE4</i> carriers.

Journal of Alzheimer's disease : JAD·2025
Same journal

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Correlates and predictors of self-efficacy among dementia caregivers: D-CARE findings.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

What should convince a clinician of disease modification in Alzheimer's disease clinical trials?

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Primary cilia-extracellular vesicle crosstalk in Alzheimer's disease: Emerging mechanisms and biomarker potential.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Evidence for progressive neurodegeneration in iatrogenic cerebral amyloid angiopathy.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
查看所有相关文章

相关实验视频

Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

生物标志物 生物标志物

Senal Peiris1, Qing Yang1, Anupa Manjitha Ekanayake Mudiyanselage1

  • 1Pennsylvania State University College of Medicine, Hershey, PA, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 26, 2025
PubMed
概括
此摘要是机器生成的。

通过PET扫描测量较高的粉样蛋白β沉积与轻度认知障碍 (MCI) 患者的认知功能较差相关. 这一发现有助于简化阿尔茨海默氏症.

更多相关视频

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

相关实验视频

Last Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.9K
Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

702

科学领域:

  • 神经成像是一种神经成像.
  • 神经学 神经学
  • 生物标志物 生物标志物

背景情况:

  • 阿尔茨海默病 (AD) 诊断依赖于MRI中观察到的解剖学变化,由于大脑体积的自然变化,这可能是模两可的.
  • 使用正子发射断层扫描 (PET) 进行的粉样蛋白成像为AD诊断提供了更准确的定量测量方法,即标准化摄取值比率 (SUVr).
  • 认知能力下降和嗅觉障碍是阿尔茨海默病的早期临床前症状,促使人们对大脑行为关系进行调查.

研究的目的:

  • 探索从PET扫描中SUVr量化的粉样β (Aβ) 沉积与正常认知 (CN) 和轻度认知障碍 (MCI) 个体的认知和嗅觉功能之间的关系.
  • 测试假设较高的Aβ沉积 (SUVr) 与较差的神经心理测试成绩有关.

主要方法:

  • 对44名受试者 (19 CN, 25 MCI) 的粉样蛋白β (Aβ) PET扫描进行了分析.
  • 标准化吸收值比率 (SUVr) 用Clinica软件计算,图像预处理和注册到T1MRI后.
  • 使用DPABI软件进行了SUVr和行为测试成绩之间的相关性分析.

主要成果:

  • 在CN和MCI组之间观察到神经心理评分和SUVr的显著差异.
  • 相关性分析显示SUVr与各种认知领域之间存在显著的关系 (p < 0.005).
  • SUVr和嗅觉功能之间的相关性并不显著.

结论:

  • 较高的粉样β沉积与患有MCI的个体认知表现较差有显著联系.
  • 嗅觉测量可能需要精细化,以提高在评估AD病理生理学的效用.
  • 这些发现表明,通过关注与粉样β沉积密切相关的指标,有可能简化AD的神经心理测试电池.