在临床上健康的成年人中,精神健康作为内皮功能障碍的保护因素
Andre Casarsa1,2, Pedro Bastos de Medeiros1,3, Julio Cesar Tolentino1,2
1Department of Internal Medicine, University Hospital Gaffrée Guinle, Federal University of the State of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
PloS one
|December 26, 2025
概括
精神健康 (SWB) 与更好的血管健康有关,独立于心理健康. 内心的平静和生活的目的是维持内皮功能和预防心血管疾病的关键因素.
科学领域:
- 心血管健康 心血管健康
- 心理神经免疫学 心理神经免疫学
- 预防医学 预防医学
背景情况:
- 内皮功能障碍 (ED) 是一种早期心血管疾病 (CVD) 标志物.
- 心理社会因素,如抑郁和焦虑影响ED.
- 精神健康 (SWB) 在血管健康中的作用尚未得到充分研究.
研究的目的:
- 在健康成年人中调查SWB和ED之间的关联.
- 控制心理健康和心血管风险因素.
- 确定与血管健康相关的精神层面.
主要方法:
- 在148名成年人 (18-60岁) 的横截面研究中.
- 评估了SWB (FACIT-Sp),抑郁症 (PHQ-9),焦虑症 (GAD-7) 和内皮功能 (FMD).
- 使用后勤回归和差别分析.
主要成果:
- 39.2%的参与者患有ED.
- SWB,BMI,焦虑和抑郁与ED有关.
- 即使排除了焦虑/抑郁症患者,SWB仍然与ED相反相关.
- 内心的平静和生活的目的,而不是信仰,杰出的个人与没有ED.
结论:
- SWB,特别是内心的平静和意义,独立地与保存的内皮功能联系在一起.
- 研究结果支持将心理社会和精神因素纳入心血管疾病风险评估.
- 促进SWB可能有助于心血管健康策略.
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