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Updated: Jan 7, 2026

High-throughput Antiviral Assays to Screen for Inhibitors of Zika Virus Replication
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High-throughput Antiviral Assays to Screen for Inhibitors of Zika Virus Replication

Published on: October 30, 2021

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奇孔古尼亚病毒复制酶突变体的转补剂揭示了阿尔法病毒复制复杂性,并支持抗病毒工具开发

Sainan Wang1, Krystyna Naumenko1,2, Mandana Mirzajani Sarvandani1

  • 1Institute of Bioengineering, University of Tartu, Tartu, Estonia.

PLoS pathogens
|December 26, 2025
PubMed
概括

奇孔古尼亚病毒 (CHIKV) 的非结构蛋白 (nsP1-nsP4) 对于RNA复制至关重要. 一项新的转补酶测定揭示了这些蛋白质之间的功能性相互依赖,有助于抗病毒查.

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