由于Mycoplasma pneumoniae感染而引起的次要急性肝炎
Luis Bachiller-Carnicero1, Laura Crespo-Valderrábano2
1Unidad de Pediatría, Centro de Salud Huerta del Rey, Área de Salud Valladolid Oeste.
Boletin medico del Hospital Infantil de Mexico
|December 26, 2025
概括
肺炎菌可引起儿童的肝炎,这是一个罕见的疾病,具有高的转氨基酶. 这一案例突出了一个患有严重超氨酸血症的儿科患者,原因是Mycoplasma pneumoniae感染,成功地用阿齐思罗米治疗.
科学领域:
- 儿科肝病学 儿科肝病学
- 传染性疾病 传染性疾病
背景情况:
- 儿童的超氨酸血症需要进行彻底的病因学研究.
- 当例行检查结果为阴性时,应考虑不常见的肝炎原因.
- 肺炎菌种很少影响肝脏,超氨基酶水平超过500 IU/l是例外情况.
研究的目的:
- 报告小儿病患患患有严重的超胺血症病例,该病例是由Mycoplasma pneumoniae引起的.
- 讨论儿科Mycoplasma pneumoniae感染中罕见的肝脏参与的诊断方法和管理.
主要方法:
- 一名5岁的孩子出现了包括白色,喘息和表胃痛在内的症状,以及显著升高的ALT和AST水平.
- 诊断工作包括 Mycoplasma pneumoniae 的血清学,自身免疫标记物和腹部超声波.
- 该患者被诊断为由于Mycoplasma pneumoniae引起的急性肝炎,并接受了azithromycin治疗.
主要成果:
- 血清学测试证实了Mycoplasma pneumoniae感染的情况.
- 自身免疫标记是负的,腹部超声波是正常的.
- 在接受了阿齐思罗米辛治疗后,患者的临床症状迅速消失,而透氨酶水平在几个月内逐渐下降.
结论:
- 由于Mycoplasma pneumoniae引起的肝脏感染,虽然很少见,但可能会出现严重的超输氨酸血症.
- 这种情况很可能是免疫介导的,通常是良性的和自我限制的.
- 排除自身免疫性肝炎至关重要,尤其是在有自身免疫性疾病家族史的情况下.
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