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Updated: Jan 7, 2026

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通过协调的P21激活激酶激活和Rab3a导向的囊泡融合来修复粉胺β诱导的血损伤

Deepak Kunhi Valappil1, Priyadarshini Veerabhadraswamy2, Prakhyath Hegde1

  • 1Manipal Institute of Regenerative Medicine, Bangalore, Manipal Academy of Higher Education, Manipal, 560064, India.

Biochimica et biophysica acta. Molecular basis of disease
|December 26, 2025
PubMed
概括

神经元通过结合的细胞外和细胞内修复来自有毒的粉样β (Aβ) 寡合体的血损伤. 这种Rab3a和pPAK1协调的修复机制对于阿尔茨海默氏症中神经元的存活至关重要.

关键词:
粉样蛋白-β的小分子.lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis 是一种发生在细胞体内发生的细胞体中发生的细胞体中发生的细胞体膜损伤会导致膜损伤.维修等离子体膜的维修拉比阿,就是拉比阿.通过p21激活的激酶酶.

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