双胞胎:基切除修复通路酶FEN1执行与NER通路有关的催化活动

Ulises Omar García-Lepe1, Sofía Gabriela Tomás-Morales1, María Teresa Izaguirre-Hernández1

  • 1Genetics and Molecular Biology Department, Centro de Investigación y de Estudios Avanzados del IPN, Av. Instituto Politécnico Nacional No. 2508, C.P. 07360, Ciudad de México, Mexico.

Biochimie
|December 26, 2025
PubMed
概括

Giardia duodenalis的DNA修复对其生命周期至关重要. 研究人员描述了Fen1酶的特征,发现它可以分裂泡DNA,帽子区域是这种活动的关键.

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